![]() The surface morphology and chemical composition of modified PDMS (PDMS-g-MPA-N⁺) were confirmed by scanning electron microscopy (SEM), energy dispersive spectrometry (EDS), and X-ray photoelectron spectroscopy (XPS). Herein, an antimicrobial coating on the surface of silicone elastomer (PDMS) has been successful constructed, which based on maleopimaric acid quaternary ammonium cation (MPA-N⁺). ![]() Therefore, constructing antimicrobial coating that exerts potent antimicrobial activity combined with low cytotoxicity is of great significance. Furthermore, various alternatives to manipulate the controlled release of bioactives from carriers and the perspective of more progress in these SR carriers are highlighted.ĭespite advanced sterilized and aseptic techniques, biomaterial-associated infections are still posing a great threat to human life. An overview of cargo release mechanisms is also discussed. In this review, we will shed light on the effect of different stimuli such as temperature, humidity, pH, light, enzymatic hydrolysis, redox, and also multiple stimuli on the release of encapsulated cargo and their potential applications in the food and pharmaceutical industries. There are various stimuli to control the favorite release of bioactives. For the food industry, release of encapsulated bioactives is considerably important in processing or storage of food products and can be used in their formulation or packaging. The potential of releasing the loaded bioactives in site-specific is of great importance for the pharmaceutical industry and medicine that can deliver the cargo in an appropriate condition. SR carriers are able to release the encapsulated bioactive compounds (bioactives) upon an external trigger. Recent advances in emerging nanocarriers and stimuli-responsive (SR) delivery systems have brought about a revolution in the food and pharmaceutical industries. The concentration of gaseous ClO2 released from the film is sufficiently high to achieve antimicrobial activity, thus enabling design of self‐sterilizing films. ![]() ![]() The film contains sodium chlorite (NaClO2) crystals and releases chlorine dioxide (ClO2) gas on demand upon UV‐activation and exposure to moisture. A polymeric film that releases a disinfectant gas in controlled quantities on demand is reported. Because both PVA and POD possess properties analogous to polymers used in packaging films, it is concluded that the approach described in this study may enable introduction of deodorizing or antimicrobial functional properties into polymeric packaging. Additionally, it is found that the half‐life of the UV‐activated state of NaClO2 depends on the reactivity of the polymer matrix. Specifically, by determining the sizes of the polymer‐dispersed NaClO2 particles, support for the hypothesis that UV light activates an interfacial layer of the NaClO2 crystals to generate ClO2 is obtained. In addition to showing that the concentration of gaseous ClO2 released from the polymeric films is sufficiently high for antimicrobial activity, fundamental insights into factors controlling ClO2 release are provided by using atomic force microscopy, optical microscopy, Raman microscopy, and time‐of‐flight secondary ion mass spectrometry. ![]() It is reported that polyvinyl alcohol (PVA) or polyolefin (POD) films that contain NaClO2 crystals can release ClO2 gas upon UV‐activation and exposure to moisture. Past attempts to create such films, however, have suffered from the need for stringent control over moisture or exposure to visible light prior to use. Polymeric films that release disinfectant gas on demand have the potential to be useful for management of microbial burden (e.g., sterilization). ![]()
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